Breathalyzer for lung cancer? new study tests AI-Powered nodule detection

NCT ID NCT06518655

Recruiting now Diagnosis Sponsor: ChromX Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study is testing whether a breath test can accurately tell the difference between benign and malignant lung nodules. Researchers will analyze volatile organic compounds (VOCs) in the exhaled breath of 3,000 people with lung nodules. The goal is to develop an AI model that could one day help doctors diagnose lung cancer earlier and more safely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: breath analysis (volatile organic compounds) via GC-MS and μGC-PID
What this could lead to: If successful, this could lead to a simple, non-invasive breath test to help doctors decide which lung nodules are cancerous without needing a biopsy.
What could go wrong: This is an early exploratory study. The breath test may not be accurate enough to replace current methods, and results may not apply to all types of nodules or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm Multiple Pulmonary Nodules pulmonary coin lesion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER PULMONARY NODULES, MULTIPLE PULMONARY NODULES, SOLITARY

Contacts and locations

Locations

First People's Hospital of Foshan
RECRUITING

Foshan, Guangdong, 528000, China
Guangzhou Development Zone Hospital
RECRUITING

Guangzhou, Guangdong, China
Huangpu District Chinese Medicine Hospital
RECRUITING

Guangzhou, Guangdong, China
Huangpu District Hongshan Street Community Health Service Center
RECRUITING

Guangzhou, Guangdong, China
Huangpu District Jiufo Street Community Health Service Center
RECRUITING

Guangzhou, Guangdong, China
Huangpu District Lianhe Street Second Community Health Service Center
RECRUITING

Guangzhou, Guangdong, China
Huangpu District Xinlong Town Central Hospital
RECRUITING

Guangzhou, Guangdong, China
Huangpu District Yonghe Street Community Health Service Center
RECRUITING

Guangzhou, Guangdong, China
Liwan District Central Hospital
RECRUITING

Guangzhou, Guangdong, 510175, China
Peking Union Medical College Hospital
RECRUITING

Beijing, Beijing Municipality, China
Renmin Hospital of Wuhan University
RECRUITING

Wuhan, Hubei, China
Shanghai Chest Hospital
RECRUITING

Shanghai, Shanghai Municipality, China
Sichuan Cancer Hospital
RECRUITING

Chengdu, Sichuan, 610042, China
The Fifth Affiliated Hospital of Guangzhou Medical University
RECRUITING

Guangzhou, Guangdong, China
The First Affiliated Hospital of Guangzhou Medical University
RECRUITING

Guangzhou, Guangdong, 510140, China

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