Breathalyzer for lung cancer? new study tests AI-Powered nodule detection

NCT ID NCT06518655

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This observational study is testing whether a breath test can accurately tell the difference between benign and malignant lung nodules. Researchers will analyze volatile organic compounds (VOCs) in the exhaled breath of 3,000 people with lung nodules. The goal is to develop an AI model that could one day help doctors diagnose lung cancer earlier and more safely.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

breath analysis (volatile organic compounds) via GC-MS and μGC-PID

What this could lead to

If successful, this could lead to a simple, non-invasive breath test to help doctors decide which lung nodules are cancerous without needing a biopsy.

What could go wrong

This is an early exploratory study. The breath test may not be accurate enough to replace current methods, and results may not apply to all types of nodules or patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm Multiple Pulmonary Nodules pulmonary coin lesion

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First People's Hospital of Foshan

    RECRUITING

    Foshan, Guangdong, 528000, China

    Contact

  • Guangzhou Development Zone Hospital

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • Huangpu District Chinese Medicine Hospital

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • Huangpu District Hongshan Street Community Health Service Center

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • Huangpu District Jiufo Street Community Health Service Center

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • Huangpu District Lianhe Street Second Community Health Service Center

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • Huangpu District Xinlong Town Central Hospital

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • Huangpu District Yonghe Street Community Health Service Center

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • Liwan District Central Hospital

    RECRUITING

    Guangzhou, Guangdong, 510175, China

    Contact

  • Peking Union Medical College Hospital

    RECRUITING

    Beijing, Beijing Municipality, China

    Contact

  • Renmin Hospital of Wuhan University

    RECRUITING

    Wuhan, Hubei, China

    Contact

  • Shanghai Chest Hospital

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact

  • Sichuan Cancer Hospital

    RECRUITING

    Chengdu, Sichuan, 610042, China

    Contact Phone: •••-•••-••••

  • The Fifth Affiliated Hospital of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, China

    Contact

  • The First Affiliated Hospital of Guangzhou Medical University

    RECRUITING

    Guangzhou, Guangdong, 510140, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••