Blood test may spot lung cancer early, avoiding unnecessary biopsies
NCT ID NCT07623473
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
The NIMBLE study is testing whether blood-based biomarkers can accurately distinguish between cancerous and non-cancerous lung nodules. Researchers will analyze blood samples from 1,800 patients referred with a lung nodule, looking at protein markers, epigenetic smoking markers, and DNA changes. The goal is to improve lung cancer diagnosis and reduce the need for invasive procedures.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Blood tests (protein tumor markers, epigenetic smoking marker, fragmentome/mutational/methylome analysis of cell-free tumor DNA)
What this could lead to
If successful, this could lead to a simple blood test that helps doctors quickly tell whether a lung nodule is cancerous or not, reducing unnecessary invasive procedures.
What could go wrong
This is an observational study, not a treatment trial. The blood tests may not be accurate enough to replace current diagnostic methods, and results may not apply to all patients.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for LUNG CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Gentofte Hospital
RECRUITINGGentofte Municipality, Denmark
Contact Phone: •••-•••-•••• Email: •••••@•••••