New combo therapy aims to keep stomach cancer from returning after surgery
NCT ID NCT07474324
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding the targeted drug disitamab vedotin to standard chemotherapy (SOX) after surgery can help prevent stomach cancer from coming back in people with HER2-positive stage III disease. About 124 adults who had complete tumor removal with extensive lymph node removal will be randomly assigned to receive either the combination or chemotherapy alone. The main goal is to see if the combination improves the chance of being cancer-free three years later.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for GC/GEJC are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The First Affiliated Hospital with Nanjing Medical University
RECRUITINGNanjing, Jiangsu, 210000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Two-Drug cocktail aims to shrink Hard-to-Treat esophageal and stomach tumors
- New drug cocktail aims to tackle Hard-to-Treat stomach cancer
- New hope for cancer patients: drug may stop dangerous weight loss before surgery
- New chemo combo could improve outcomes for stomach cancer patients
- Immunotherapy plus chemo shows promise against tough stomach cancer