Could a 7-Day cocktail beat h. pylori? new trial tests shorter fix
NCT ID NCT07232095
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a 7-day combination of vonoprazan, high-dose amoxicillin, and bismuth can effectively eradicate H. pylori bacteria in the stomach. About 316 adults with a first-time H. pylori infection will be randomly assigned to either the 7-day triple therapy or a standard 14-day dual therapy. The goal is to see if the shorter regimen works just as well with fewer side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Vonoprazan, Amoxicillin, and Bismuth
What this could lead to
If successful, this 7-day triple therapy could offer a shorter, effective first-line treatment for H. pylori infection, potentially improving patient compliance.
What could go wrong
This is a phase 4 trial, but the shorter regimen may still fail to achieve adequate eradication rates, and bismuth can cause side effects like dark stools or nausea.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The First Affiliated Hospital with Nanjing Medical University
RECRUITINGNanjing, Jiangsu, 210029, China
Contact Phone: •••-•••-•••• Email: •••••@•••••