New acid blocker may beat standard treatment for stomach bug
NCT ID NCT07537634
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a newer acid-reducing drug (vonoprazan) works better than a standard one (esomeprazole) for clearing H. pylori, a bacteria that can cause stomach ulcers and indigestion. About 80 adults with H. pylori will take one of the two drug combinations for 14 days. Four weeks later, a stool test will check if the infection is gone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
vonoprazan or esomeprazole, each combined with amoxicillin and levofloxacin
What this could lead to
If vonoprazan works better, it could offer a more effective option for clearing H. pylori infections, reducing the risk of ulcers and stomach issues.
What could go wrong
This is a small, early-phase 4 trial with only 80 participants, so results may not apply to everyone. Both regimens include antibiotics, which can cause side effects like diarrhea or allergic reactions.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Bangabandhu Sheikh Mujib Medical University
NOT_YET_RECRUITINGDhaka, Bangladesh
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Bangabandhu Sheikh Mujib Medical University
RECRUITINGDhaka, Bangladesh
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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