Which antibiotic combo wins against h. pylori? a Head-to-Head test
NCT ID NCT07746934
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial compares two 14-day antibiotic combinations for treating Helicobacter pylori, a common stomach bacteria that can cause ulcers and stomach cancer. One combination uses metronidazole, the other uses a similar drug called tinidazole. The study will see if tinidazole is just as effective at eradicating the infection, while also comparing side effects and tolerability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Tinidazole-based bismuth quadruple therapy (tinidazole, esomeprazole, tetracycline, bismuth subcitrate) compared to metronidazole-based bismuth quadruple therapy
- What this could lead to
- If tinidazole works as well as metronidazole, doctors may have another effective option for treating H. pylori infections, potentially with fewer side effects.
- What could go wrong
- This is a head-to-head comparison, not a new drug discovery. The outcome depends on real-world effectiveness and tolerability, and results may not apply to all populations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University of Medicine and Pharmacy at Ho Chi Minh City
Ho Chi Minh City, Ho Chi Minh, 70000, Vietnam
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Simpler h. pylori treatment could reduce antibiotic use