Simpler h. pylori treatment could reduce antibiotic use
NCT ID NCT07624422
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a simpler two-drug treatment (vonoprazan plus one antibiotic) works as well as a three-drug treatment (vonoprazan plus two antibiotics) for H. pylori infection. About 150 adults with confirmed H. pylori will take either regimen for 14 days. The main goal is to see how many people are cured of the infection, while also tracking side effects and how well patients follow the treatment.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Vonoprazan (a stomach acid reducer) combined with antibiotics (amoxicillin, levofloxacin, tinidazole)
- What this could lead to
- If successful, this could show that a simpler, two-drug regimen is as effective as a three-drug regimen for treating H. pylori, potentially reducing side effects and antibiotic resistance.
- What could go wrong
- This is a small, early-stage trial (phase 4) with only 150 participants. The results may not apply to everyone, and the simpler regimen might not work as well in real-world settings.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
General Assembly of Damascus Hospital
Damascus, Syria
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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