New stomach acid drug could boost h. pylori cure rates

NCT ID NCT06851468

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This completed study tested whether a new drug called keverprazan, combined with the antibiotic amoxicillin, can effectively treat a first-time H. pylori infection in adults. 264 participants took either keverprazan or esomeprazole (a standard acid reducer) plus amoxicillin for 14 days. Researchers measured how many people were cured and tracked side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Keverprazan (a drug that reduces stomach acid, similar to esomeprazole)

What this could lead to

If successful, keverprazan could offer a new treatment option for first-time H. pylori infections, potentially improving eradication rates.

What could go wrong

This is a completed trial, but results are not yet published. The study is relatively small (264 participants) and only includes first-time infections, so findings may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • KeyLabGIDiseasesGansu

    Lanzhou, Gansu, 730000, China