Cure My Disease

Don't miss your cure!

 Log in / Sign up

Shorter h. pylori treatment shows promise in new trial

NCT ID NCT05371249

Completed Disease control Sponsor: Fu Jen Catholic University Hospital Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This trial tests whether a 7-day course of vonoprazan combined with high-dose amoxicillin and clarithromycin can eradicate H. pylori infection as effectively as the current 14-day extended sequential therapy. About 628 adults with H. pylori infection will be randomly assigned to one of the two treatments. The main goal is to compare eradication rates, with secondary focus on side effects and how well patients follow the regimen.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
vonoprazan, amoxicillin, and clarithromycin combination
What this could lead to
If successful, this could offer a shorter, simpler treatment option for H. pylori infection with similar or better eradication rates.
What could go wrong
This is a phase 4 trial comparing existing treatments, so the new regimen may not prove superior and could have side effects like any antibiotic therapy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HELICOBACTER PYLORI are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Helicobacter pylori infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HELICOBACTER PYLORI

Contacts and locations

Locations

  • Fu Jen Catholic University Hospital

    New Taipei City, 243, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.