New MRI technique could spot hidden heart risks without radiation

NCT ID NCT07400406

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new MRI technique that uses a special iron-based contrast agent (ferumoxytol) to detect calcium buildup in heart arteries. Researchers will compare this method to standard CT scans in 100 adults with known calcified arteries. The goal is to see if the MRI can accurately measure artery blockages, potentially offering a radiation-free alternative for diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ferumoxytol (iron oxide nanoparticles)

What this could lead to

If successful, this could offer a more accurate, radiation-free way to diagnose coronary artery calcification, potentially improving heart disease detection.

What could go wrong

This is an early-stage, single-center study with only 100 participants. The new MRI method may not prove more accurate than existing CT scans, and ferumoxytol can cause allergic reactions or other side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

coronary atherosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Affiliated Hospital of Nanjing Medical University

    RECRUITING

    Nanjing, Jiangsu, 210000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••