New MRI technique could spot hidden heart risks without radiation

NCT ID NCT07400406

Recruiting now Diagnosis Sponsor: The First Affiliated Hospital with Nanjing Medical University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new MRI technique that uses a special iron-based contrast agent (ferumoxytol) to detect calcium buildup in heart arteries. Researchers will compare this method to standard CT scans in 100 adults with known calcified arteries. The goal is to see if the MRI can accurately measure artery blockages, potentially offering a radiation-free alternative for diagnosis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Ferumoxytol (iron oxide nanoparticles)
What this could lead to: If successful, this could offer a more accurate, radiation-free way to diagnose coronary artery calcification, potentially improving heart disease detection.
What could go wrong: This is an early-stage, single-center study with only 100 participants. The new MRI method may not prove more accurate than existing CT scans, and ferumoxytol can cause allergic reactions or other side effects.

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Conditions

The condition(s) this trial relates to.

coronary atherosclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CORONARY ARTERY CALCIFICATION

Contacts and locations

Locations

First Affiliated Hospital of Nanjing Medical University
RECRUITING

Nanjing, Jiangsu, 210000, China

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