Could a better blood pressure reading save kidneys?

NCT ID NCT05163158

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tested whether using central blood pressure (measured near the heart) instead of the usual arm cuff leads to better outcomes in 116 people with advanced chronic kidney disease. Participants were randomly assigned to either a central BP target or a standard arm BP target, both aiming for under 130 mmHg. The goal was to see if this approach is feasible and reduces artery stiffness after 12 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Central blood pressure measurement
What this could lead to
If successful, this could show that using central blood pressure readings leads to better blood pressure management and fewer heart and kidney complications in advanced kidney disease patients.
What could go wrong
This is a small pilot study focused on feasibility, not on proving clinical benefits. The results may not confirm that central BP targeting is better than standard care, and larger trials are needed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hôpital du Sacré-Coeur de Montréal

    Montreal, Quebec, H4J1C5, Canada

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