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Hidden kidney damage may lurk in rheumatoid arthritis patients

NCT ID NCT07805109

Knowledge-focused Sponsor: Assiut University Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 04, 2026 · Last updated Sep 09, 2026 · Updated 1 time

Summary

Researchers are testing whether people with rheumatoid arthritis have early, symptom-free kidney problems more often than healthy people of the same age and sex. The study compares kidney function and urine protein levels between 120 participants, including those with rheumatoid arthritis and matched healthy controls. The goal is to see if hidden kidney damage relates to how active the arthritis is, which could lead to earlier detection and care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If it works, this could point toward routine kidney screening for people with rheumatoid arthritis, catching damage before symptoms appear.
What could go wrong
This is an observational study, not a treatment trial. It may not prove that rheumatoid arthritis causes kidney damage, only that the two are linked.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Jun 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with rheumatoid arthritis attending the Rheumatology outpatient clinic and inpatient wards at Assiut University Hospitals, and age- and sex-matched healthy controls.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18 years or older * For patient group: Diagnosis of rheumatoid arthritis according to the 2010 ACR/EULAR classification criteria * For control group: Age- and sex-matched apparently healthy individuals with no history of autoimmune disease or chronic kidney disease * Willingness to provide written informed consent Exclusion Criteria: * Known chronic kidney disease * Acute kidney injury * Diabetes mellitus * Uncontrolled hypertension * Active urinary tract infection * Pregnancy * History of obstructive uropathy or renal stones * Systemic lupus erythematosus or other connective tissue diseases * Malignancy * Patients on maintenance hemodialysis

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome kidney failure rheumatoid arthritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic kidney diseases Renal dysfunction Rheumatoid arthritis

How to take part

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  1. The official record

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