New pill could ease sleep apnea and lower blood pressure

NCT ID NCT06785454

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 30 times

Summary

This study tested a daily pill called lorundrostat in 48 adults with moderate-to-severe obstructive sleep apnea and high blood pressure. The goal was to see if the drug could reduce breathing pauses during sleep and lower nighttime blood pressure. Participants took the drug or a placebo for 4 weeks, then switched. The trial is complete, and results will show if the drug helps control both conditions.

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Contacts and locations

Locations

  • Arrow Clinical Trials

    Daytona Beach, Florida, 32117, United States

  • CNS Healthcare - Memphis (Clinical Neuroscience Solutions - Memphis)

    Memphis, Tennessee, 38119, United States

  • CNS Healthcare - Orlando (Clinical Neuroscience Solutions)

    Orlando, Florida, 32801, United States

  • CTI Clinical Research Center

    Cincinnati, Ohio, 45212, United States

  • Centennial Medical Group

    Columbia, Maryland, 21045, United States

  • Centricity Research Rincon Pulmonology

    Rincon, Georgia, 31326, United States

  • Chandler Clinical Trials

    Chandler, Arizona, 85224, United States

  • Chicago Research Center Inc

    Chicago, Illinois, 60634, United States

  • Clayton Sleep Institute

    St Louis, Missouri, 63123, United States

  • Healthcare Research Network

    Hazelwood, Missouri, 63042, United States

  • Henry Ford Health System/Henry Ford Medical Center - Columbus

    Novi, Michigan, 48377, United States

  • Huntsville Research Institute LLC

    Huntsville, Texas, 77340, United States

  • NeuroTrials Research Inc

    Atlanta, Georgia, 30328, United States

  • Northwest Research Center

    Portland, Oregon, 97202, United States

  • Nouvelle Clinical Research

    Cutler Bay, Florida, 33189, United States

  • Orange County Research Institute

    Anaheim, California, 92801, United States

  • Patient First MD

    Middletown, New Jersey, 07748, United States

  • PharmaDev Clinical Research Institute, LLC

    Miami, Florida, 33176, United States

  • Preferred Research Partners Inc.

    Little Rock, Arkansas, 72211, United States

  • Probe Clinical Research Corporation

    Riverside, California, 92501, United States

  • Research Carolina Elite

    Denver, Colorado, 28037, United States

  • Revive Research Institute, Inc

    Southfield, Michigan, 48075, United States

  • Sleep Therapy Research Center

    San Antonio, Texas, 78229, United States

  • The Neurology Center of Southern California - Profound Research, LLC

    Carlsbad, California, 92011, United States

  • The University of Alabama

    Tuscaloosa, Alabama, 35401, United States

  • University of Washington

    Seattle, Washington, 98104, United States

  • Velocity Clinical Research, Rockville

    Rockville, Maryland, 20854, United States

Conditions

Explore the condition pages connected to this study.