HYPERTENSION

This study is testing whether a non-invasive brain stimulation technique can safely help regulate blood pressure in people with either high or low blood pressure. Researchers will enroll 25 participants to receive this experimental stimulation treatment. The goal is to see if thi…

This study aims to find out which of two exercise programs is better for improving heart health and reducing inflammation in women who have both obesity and high blood pressure. Researchers will compare steady, moderate exercise with a faster-paced interval program over 8 weeks. …

This study aims to see if the medication eplerenone improves heart blood flow and structure better than the medication chlorthalidone in women who had preeclampsia during pregnancy and now have ongoing high blood pressure. About 90 participants will take one of the two study drug…

This study aims to compare the effectiveness and safety of two different blood pressure medications, sacubitril/allisartan and amlodipine, in adults who are overweight or obese and have high blood pressure. About 104 participants will take one of the two medications daily for 8 w…

This study will test whether a large language model (like a sophisticated AI chatbot) can help community doctors better coordinate care for adults with high blood pressure plus either diabetes or high cholesterol. It will compare the AI-assisted management approach to standard ca…

This study tests whether community health workers can help people better manage multiple chronic conditions like diabetes, high blood pressure, and heart disease. 300 adults with at least two chronic health conditions will work with trained health coaches for 9 months to develop …

This study is testing if choosing blood pressure medicine based on a person's unique body fluid flow patterns works better than following standard guidelines. It will involve 240 adults with mild to moderate high blood pressure who haven't taken medication before. Researchers wil…

This study aims to see if two different types of strength training are practical and safe for older adults with high blood pressure, and if they might improve heart health, mood, and fitness. Researchers will assign 60 participants to either dynamic training (moving weights) or i…

This study is testing whether a computer tool that gives doctors treatment suggestions during appointments helps lower patients' high blood pressure more effectively than usual care. It will involve 168 adults whose blood pressure is still high despite taking medication. The main…

This study tests whether a combination of a digital food marketplace, personalized dietitian coaching, and home blood pressure monitoring can help lower blood pressure. It will involve 100 Black and Hispanic adults with high blood pressure who live in areas with limited access to…

This study is testing a 9-month support program to help new mothers improve their heart health after a first pregnancy complicated by preeclampsia. The program uses a special smartphone app for tracking blood pressure and weight, along with online coaching and group meetings. Res…

This study is testing whether a combination of telehealth video visits and home blood pressure monitoring can safely manage chronic high blood pressure during pregnancy. It will compare this approach to the standard care of frequent in-person clinic visits. The goal is to see if …

This study is testing a new workplace program designed to help adults with newly diagnosed high blood pressure. It will compare the program, which includes lifestyle support and reminders, to standard workplace health advice. The goal is to see if this approach helps people bette…

This study aims to see if one of two common progestin-only birth control pills (norethindrone or drospirenone) is better at helping control high blood pressure in women recovering from preeclampsia after giving birth. It will involve 50 women at OHSU who have had preeclampsia and…

This study aims to find which combination of blood pressure medications works better for women with high blood pressure after giving birth. Researchers will compare two different drug pairs in 200 postpartum women who need additional treatment beyond their initial medication. The…

This study is testing if a one-time procedure called renal denervation can safely lower high diastolic blood pressure. The procedure uses a catheter to disrupt nerves near the kidneys that help regulate blood pressure. Researchers will compare the real procedure against a sham (f…

This study is testing an investigational drug called VCT220 to see if it is safe and effective for treating high blood pressure in people who are also overweight or have obesity. It will involve about 160 adults and compare the drug's effects against a placebo over 20 weeks. The …

This study is testing a new long-acting injectable medication called IBI3016 for people with mild to moderate high blood pressure. About 352 participants will receive either the drug or a placebo as an injection under the skin every 3 or 6 months for up to 2 years. The main goal …

This study aims to see if exercise can be a safe, drug-free way to help control blood pressure in people with glaucoma and high blood pressure. Researchers will test 60 participants to compare how different types of exercise (like aerobic or strength training) done at different t…

This study aims to find out if using a low-sodium salt substitute is safe for adults with high blood pressure who are taking medication. Researchers will check if the salt swap causes dangerously high potassium levels or helps correct low potassium. About 600 participants in Bang…

This study is testing a digital tool called a 'Smart Family Doctor' that uses AI to help people manage their health after heart surgery or stents. It aims to see if the app helps patients better control their blood pressure, blood sugar, and cholesterol. The trial will involve ab…

This study is testing whether a smartphone app that reminds people to take their medication and check their blood pressure helps them manage their high blood pressure better. It will compare 40 adults with high blood pressure, where half use the app and a special blood pressure m…

This study is testing whether a special clinic where heart, kidney, and diabetes doctors work together as a team can help people with type 2 diabetes and heart disease. It will compare this team approach to usual primary care to see if it improves blood pressure and cholesterol c…

This study is testing whether a supplement made from Nigella sativa (black cumin seed) can help lower blood pressure in women with borderline high readings. Researchers will compare the supplement against a placebo in 106 women over 12 weeks. The goal is to see if this natural pr…

This study is testing a new system that creates easy-to-read reports from patients' fitness tracker data. The goal is to help primary care doctors give better, more personalized advice about physical activity to patients with borderline or mild high blood pressure. Researchers wi…

This study is testing a new digital care program where nurses remotely help patients manage their heart health. Participants with high blood pressure or cholesterol will use home devices to track their numbers, and nurses will provide guidance. The goal is to see if this approach…

This study is testing a medical device designed to lower dangerously high blood pressure in the lungs of people with heart failure. Researchers will compare the device procedure to a placebo procedure in 750 participants who are already on the best available heart medications. Th…

This study is testing whether a new medication called TCA108 can help lower blood pressure in adults whose high blood pressure isn't well controlled with their current medications. Researchers will enroll 400 adults who still have high blood pressure despite taking two different …

This study is testing whether providing different amounts of monthly grocery money helps low-income people with diabetes or high blood pressure better manage their health. About 4,450 participants will be randomly assigned to receive either an $80 or $120 monthly food card for on…

This study is testing a new program where hair stylists in beauty salons are trained to check blood pressure and help connect their clients to health resources. It aims to see if this community-based approach helps Black and Hispanic women better manage their high blood pressure.…

This study is testing a community-based education and support program designed to help adults in Bangladesh better manage their high blood pressure. The program, delivered by local health workers, teaches about diet, exercise, and medication, and provides tools like blood pressur…

This study aims to find the best combination of cardio and strength training to improve heart health, body composition, and menopause symptoms in active postmenopausal women. Over 20 weeks, 60 participants will try different workout schedules to see which mix delivers the most be…

This study is testing whether a supervised, community-based exercise program can help older adults with multiple chronic conditions improve their health and quality of life. It will enroll 150 people aged 50 and older who have at least two conditions like heart disease risk, diab…

This study is testing a medication called osilodrostat to see if it can help control high blood pressure in adults with Cushing's syndrome, a condition caused by too much of the stress hormone cortisol. For 30 weeks, about 63 participants will receive either the real drug or a pl…

This study is testing whether regular phone counseling can help adults with high blood pressure better manage their condition. About 320 patients will either receive brief phone check-ins every two weeks for three months or continue with their usual hospital care. Researchers wan…

This study tests if pharmacists can help patients and doctors use simpler, combined blood pressure pills. It aims to see if this approach helps patients better control their blood pressure. The trial will involve about 750 people with high blood pressure who are not yet on the co…

This study aims to see if combining a Mediterranean diet with intermittent fasting can help control high blood pressure. It will involve 48 adults in Turkey who are newly diagnosed with hypertension. Researchers will compare the effects of these dietary approaches to understand w…

This is a small, early-stage study to see if taking a specific probiotic supplement for 10 weeks can help lower blood pressure in middle-aged Chinese adults with untreated high blood pressure. Researchers will enroll 30 participants to test if the treatment is feasible and gather…

This study is testing a new computer-based decision tool designed to help doctors better protect cancer survivors from heart problems. The tool will be tested with 60 cancer survivors who are at risk for heart disease. Researchers want to see if the tool is easy for doctors and p…

This study is testing if a new 'smart' approach helps doctors choose the right blood pressure medication for each person. It uses a special blood test and computer analysis to give doctors extra information when making their choice. The trial will involve 400 adults with high blo…

This study is testing if a group-based care model can help people in Nepal better manage high blood pressure and diabetes. About 1,110 adults with these conditions will be assigned to either continue their usual care or join a new program with monthly group sessions for education…

This VA program aims to help clinics better provide proven health services for women Veterans in midlife. It will test two different support strategies across at least 18 VA facilities to help them offer trauma-informed care, menopause symptom therapy, and weight management progr…

This study tests whether a new care coordination program helps cancer patients better manage chronic conditions like high blood pressure, diabetes, and high cholesterol during cancer treatment. Researchers will compare patients who receive the new program to those getting usual c…

This study will test whether Songling Xuemaikang capsules, a traditional Chinese herbal medicine, can help control cerebral small vessel disease in people with high blood pressure. Researchers will enroll 90 participants aged 55-75 who have both conditions and randomly assign the…

This study is testing whether giving people with high blood pressure personalized lifestyle advice based on a detailed questionnaire works better than standard advice. Researchers will compare two groups of 64 adults to see which approach lowers blood pressure more over three mon…

This study is testing whether a 'food is medicine' program can help adults with high blood pressure and obesity. For 24 weeks, half the participants will receive weekly deliveries of heart-healthy meals and cooking lessons, while the other half receives usual care. Researchers wa…

This study aims to help people living with HIV who have their virus under control but struggle with high blood pressure. Researchers will design and test a support program to help participants take their blood pressure medication more consistently. The goal is to improve blood pr…

This study is testing a new support package for older adults who have two or more long-term health problems, like high blood pressure, diabetes, or arthritis. The package includes digital tools, personalized guidance, and ongoing support to help manage their health. Researchers w…

This study tests whether changing how blood pressure medications appear in doctors' electronic health record systems increases prescriptions for preferred combination pills. Researchers will modify 50 primary care clinics' computer systems to either show combination medications a…

This study aims to test whether the Oura Ring's special algorithm can accurately identify signs of high blood pressure (hypertension). It will observe 2 million existing Oura Ring users in the U.S. to see how well the ring's readings match what users report about their own blood …

This study is testing a new wrist-worn device (Hilo band) that continuously measures blood pressure. Researchers want to see how well it compares to a standard arm-cuff monitor worn for 24 hours. About 330 adults in Switzerland will wear both devices for a day to collect data and…

This study aims to find undiagnosed or poorly controlled high blood pressure and glaucoma in adults aged 40 and older living in New York City affordable housing. Researchers will screen over 7,000 people and test if a virtual assistant that sends reminders and health information …

This study aims to see if mindfulness training for pregnant women can help reduce stress for both mother and baby. Researchers will measure how 40 mother-baby pairs respond to stress at 6 months old and check markers of heart disease risk at 12 months. The goal is to understand i…

This study is testing if a powder containing potassium, magnesium, and citrate, mixed into water, can help lower blood pressure in African American adults with early-stage or borderline high blood pressure. Researchers want to see if this supplement can mimic the benefits of a sp…

This small pilot study is testing whether carefully managing two common health issues—high blood pressure and high cholesterol—can help prevent dementia in people who are genetically at risk. It will enroll 10 adults aged 50-75 who carry a specific gene linked to higher dementia …

This study aims to see if a daily blood pressure medication called enalapril is better at protecting women's long-term heart health after a high-blood-pressure pregnancy (like preeclampsia) than the medications doctors currently use. It will involve 60 women who have recently giv…

This study aims to see if a single session of laser acupuncture can lower high blood pressure in patients receiving dialysis for kidney failure. It will involve 60 adult patients. Researchers will measure blood pressure before and after the non-invasive laser treatment to check f…

This study aims to improve a system that helps doctors identify physically inactive patients and refer them to local exercise programs. It will test new support methods for clinics to see if they can get more eligible patients connected to these community resources. The goal is t…

This study looks back at existing medical records to understand how high blood pressure is treated in Brazil's public healthcare system. Researchers will analyze data from 15,000 patients to see if treatment follows guidelines and identify delays in care. The goal is to learn abo…

This study aims to understand how a 12-week supervised exercise program benefits the hearts of older adults with high blood pressure. Researchers will enroll 42 sedentary participants and randomly assign them to either follow the exercise program or not. The main goal is to ident…

This early-stage study aims to see how three new experimental drugs interact when taken together by healthy volunteers. It will measure how the body processes these drugs and check for safety. The results will help researchers decide if they should develop these drugs further for…

This early-stage study aims to understand how two new experimental drugs for high blood pressure interact when taken together. Researchers will give both drugs to 41 healthy adult volunteers to measure how the body processes them and check for safety. The goal is to gather basic …

This study aims to understand how drinking coffee versus hibiscus tea affects blood pressure and heart rate during long periods of sitting. Thirty healthy, inactive adults will try both beverages on separate occasions while researchers measure their heart health. The goal is to g…

This study aims to find out if popular over-the-counter mouthwashes, while cleaning teeth and gums, might also harm the good bacteria in your mouth and potentially affect heart health. Researchers will test 200 people, with and without gum disease, using different mouthwash ingre…

This study aims to understand how nighttime blood pressure patterns affect the heart's electrical activity and pumping function in people with high blood pressure. Researchers will observe 140 adults with hypertension, measuring their blood pressure over 24 hours and performing h…