Zapping kidney nerves: a Needle-Free hope for high blood pressure?

NCT ID NCT07664787

Not yet recruiting Disease control Sponsor: Ruijin Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests a new device that uses radiofrequency energy to calm overactive kidney nerves, which can drive high blood pressure. Twenty adults with untreated mild hypertension will either get the real procedure or a sham (fake) one. The main goal is to see if the real treatment safely lowers 24-hour blood pressure more than the sham at 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Six-channel radiofrequency ablation system (device) for renal denervation
What this could lead to: If successful, this could offer a drug-free alternative to control early-stage high blood pressure, potentially reducing long-term medication needs.
What could go wrong: This is a very small pilot study (20 people) with no phase, so results are preliminary. The procedure involves risks like bleeding or vessel damage, and it may not lower blood pressure enough to be worthwhile.

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Conditions

The condition(s) this trial relates to.

essential hypertension follicular lymphoma hypertensive disorder tumor grade 1, general grading system

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GRADE 1 HYPERTENSION

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