Can a common heart drug shield breast cancer patients from Surgery-Related heart damage?

NCT ID NCT07583134

Not yet recruiting Disease control Sponsor: Chang-Ik Yoon Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether the drug propranolol can prevent heart injury after breast cancer surgery in women who also have high blood pressure or angina. One hundred participants will either receive propranolol before surgery or standard care. Researchers will measure heart stress using blood tests and examine tumor samples.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: propranolol (a beta-blocker drug)
What this could lead to: If it works, this could point toward a simple way to protect the heart during breast cancer surgery for patients with high blood pressure or chest pain.
What could go wrong: This is a small, early-phase trial with only 100 people. It may not show a clear benefit, and propranolol can cause side effects like low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm hypertensive disorder intermediate coronary syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BREAST CANCER MYOCARDIAL INJURY AFTER NONCARDIAC SURGERY (MINS)

Contacts and locations

Locations

Seoul St. Mary's Hospital, The Catholic University of Korea

Seoul, Seoul, 06591, South Korea

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