Could a faster pacemaker setting boost heart and brain health?

NCT ID NCT07589452

Not yet recruiting Disease control Sponsor: Medtronic Cardiac Rhythm and Heart Failure Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether setting a pacemaker to a personalized rate of 75 beats per minute, instead of the usual 50-60, can improve heart function and blood flow to the brain in people with high blood pressure and a slow heart rate. About 70 patients aged 65 and older will be randomly assigned to either the personalized rate or standard rate. Researchers will measure changes in heart function and brain blood flow after 3 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: pacemaker with personalized lower rate (75 bpm)
What this could lead to: If it works, this could point toward a better way to set pacemakers for hypertensive patients, potentially improving heart and brain function.
What could go wrong: This is a small, early-stage study with only 70 participants, so results may not apply to everyone. The personalized rate may not provide clear benefits over standard settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Bradycardia hypertensive disorder sick sinus syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRADYCARDIA

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