Can we silence the hormone behind high blood pressure?

NCT ID NCT07748975

Not yet recruiting Knowledge-focused Sponsor: DejthidaNathaphong Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study reviews existing research to understand how aldosterone, a hormone that regulates blood pressure, contributes to hypertension. It looks at the proteins and genetic factors involved in aldosterone production and how the body's signals might be able to block its effects. The goal is to identify new ways to treat high blood pressure by targeting these pathways.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Aldosterone circulation diagnostic test, medication, and surgical procedures
What this could lead to: If successful, this could clarify how aldosterone triggers hypertension and identify new targets for silencing its effects, potentially improving treatment strategies.
What could go wrong: This is a review of existing studies, not a new treatment trial. Findings may be limited by the quality and variability of the included data, and no direct patient benefit is guaranteed.

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Conditions

The condition(s) this trial relates to.

hypertensive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALDOSTERONE SYNTHASE ALDOSTERONEMIA BETA-CATENIN CYP11B1 CYP11B2 HYPERTENSION

Contacts and locations

Locations

Investigation Center

Vadhana, Bangkok, 10110, Thailand

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