New blood pressure drug takes on amlodipine in overweight patients
NCT ID NCT07241338
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a newer blood pressure drug, sacubitril/allisartan, to the standard drug amlodipine in 104 overweight or obese adults with high blood pressure. Participants will take one of the two drugs for 8 weeks, with dose adjustments if needed. The main goal is to see which drug lowers systolic blood pressure more effectively.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sacubitril/allisartan (a blood pressure drug) and amlodipine (a standard blood pressure drug)
- What this could lead to
- If it works, this could show that sacubitril/allisartan is a better option for controlling blood pressure in people who are overweight or obese.
- What could go wrong
- This is a small, early-phase trial with only 104 participants and an 8-week duration, so results may not apply to everyone. It is also open-label, meaning both doctors and patients know which drug is given, which can bias results.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Peking University People's Hospital
Beijing, China
Contact Email: •••••@•••••
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