Can a new blood pressure pill match the original?

NCT ID NCT07748702

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This trial is testing two experimental versions of a blood pressure drug, called D311 and D107, against the original medication, CKD-339. Healthy adults aged 19 to 55 will receive a single dose of each version in a random order to compare how the drug is absorbed and processed in the body, and to check for any safety concerns. The goal is to see if these new versions behave similarly to the original, which could lead to more options for managing high blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
CKD-339 (an experimental hypertension drug) and two test versions, D311 and D107
What this could lead to
If successful, this could support the development of a new formulation of a blood pressure medication that is as safe and effective as the existing one, potentially offering more options for treating hypertension.
What could go wrong
This is an early-phase study in healthy volunteers, not people with hypertension. It focuses on how the drug is processed and safety, not on lowering blood pressure. Results may not predict real-world effectiveness or long-term safety.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bumin Hospital

    Seoul, South Korea

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Other studies related to the condition(s) this trial covers.