Can we stop early artery aging in kids with kidney disease?

NCT ID NCT07768865

First seen Aug 17, 2026 ยท Last updated Aug 17, 2026

Summary

This study investigates why arteries stiffen and harden faster in children and young people with chronic kidney disease (CKD) and high blood pressure. Researchers will use non-invasive tests to compare arterial stiffness between those with CKD and matched controls, including healthy peers and those with high blood pressure alone. The goal is to understand whether the stiffness is due only to high blood pressure or also to other factors like nerve activity and metabolic changes. This could help find ways to prevent or treat arterial stiffness and protect future heart and kidney health.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could identify ways to prevent or treat arterial stiffness in young people with kidney disease, potentially protecting their heart and kidney health in later life.
What could go wrong
This is an observational study, so it won't directly test a treatment. The findings may not lead to immediate clinical changes, and the results depend on the specific group of participants studied.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Evelina London Children's Hospital and Guys and St Thomas' NHS Foundation Trust

    RECRUITING

    London, Greater London, SE1 7EH, United Kingdom

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