Can black seed capsules tame borderline high blood pressure in women?

NCT ID NCT07494279

Not yet recruiting Disease control Sponsor: Liaquat University of Medical & Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a daily black seed extract supplement (Nisatol®) can help lower blood pressure in women with borderline high readings or a specific nighttime blood pressure pattern. 106 women will take either the supplement or a placebo for 12 weeks. Researchers will measure changes in blood pressure and heart rate to see if the supplement offers a natural way to manage early hypertension.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Nigella sativa (black seed) extract, standardized as Nisatol®
What this could lead to: If it works, this could point toward a natural supplement option for managing borderline high blood pressure in women without needing prescription drugs.
What could go wrong: This is a small, early-stage trial with only 106 women, so results may not apply to everyone. Supplements can have variable effects and may not lower blood pressure enough to be clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HYPERTENSION are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

benign essential hypertension hypertensive disorder Prehypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTENSION PREHYPERTENSION

Contacts and locations

Locations

University of Rome Tor Vergata

Roma, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.