One pill to tackle two heart risks: new combo therapy tested
NCT ID NCT07564726
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This completed Phase 3 trial tested whether a single pill combining ezetimibe, rosuvastatin, and amlodipine can safely lower both cholesterol and blood pressure in 163 Korean adults with hypertension and high cholesterol. Participants took the combination pill or a control for 8 weeks. The study measured changes in LDL cholesterol and systolic blood pressure to see if the combo works better than separate treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ezetimibe/Rosuvastatin and Amlodipine combination pill
- What this could lead to
- If successful, this could offer a convenient once-daily pill that manages both high cholesterol and high blood pressure, potentially improving treatment adherence.
- What could go wrong
- This is a completed Phase 3 trial with 163 participants, so results are limited to this specific group. The combination may not work for everyone and could cause side effects like muscle pain or dizziness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Asan Medical Center
Seoul, South Korea
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Cha University Bundang Medical Center
Seongnam, South Korea
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Chonnam National University Hospital
Gwangju, South Korea
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Daegu Catholic University Medical Center
Daegu, South Korea
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Dankook University Hospital
Cheonan, South Korea
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Gachon University Gil Medical Center
Incheon, South Korea
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Hallym University Sacred Heart Hospital
Anyang, South Korea
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Jeonbuk National University Hospital
Jeonju, South Korea
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Kangbuk Samsung Hospital
Seoul, South Korea
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Keimyung University Dongsan Medical Center
Daegu, South Korea
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Korea University Anam Hospital
Seoul, South Korea
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Korea University Ansan Hospital
Ansan, South Korea
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Korea University Guro Hospital
Seoul, South Korea
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Kosin University Gospel Hospital
Busan, South Korea
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Nowon Eulji Medical Center, Eulji University
Seoul, South Korea
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Pusan National University Hospital
Busan, South Korea
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Severance Hospital
Seoul, South Korea
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The Catholic University of Korea Seoul St. Mary's Hospital
Seoul, South Korea
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The Catholic University of Korea Uijeongbu St. Mary's Hospital
Uijeongbu-si, South Korea
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Uijeongbu Eulji Medical Center, Eulji University
Uijeongbu-si, South Korea
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Yeungnam University Hospital
Daegu, South Korea
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