HYPERCHOLESTEROLEMIA

This study aims to see how well patients in Italy stick with their prescribed bempedoic acid treatment for high cholesterol in everyday life. It will enroll 1,500 adults already taking the medication to track how consistently they take it and how much it lowers their 'bad' LDL ch…

This study is testing if a time-saving workout using whole-body muscle stimulation (WB-EMS) can help lower resting blood pressure and improve other heart health markers. It will involve 42 adults aged 50+ who have mild high blood pressure and are overweight. The goal is to see if…

This early-stage study is testing the safety of a new, one-time gene-editing treatment called VERVE-201. It is designed for people with dangerously high cholesterol and triglycerides that don't respond well to standard medications. The treatment works by editing a gene in the liv…

This study tests two different church-based programs to help reduce heart disease risk in Black adults in New Orleans. It will compare a program led by trained community health workers, which includes coaching and support, to a simpler group education program. The goal is to find…

This study aims to see which of two food supplements, Cynacol or Metacol, is better at lowering 'bad' cholesterol (LDL-C) over 90 days. It will involve 40 adults with mildly high cholesterol who are not on other cholesterol medications. Researchers will compare changes in cholest…

This study aims to see how well patients in Italy stick with and respond to a cholesterol-lowering injection called inclisiran in everyday life, outside of a controlled clinical trial. It will enroll 3000 adults already receiving the treatment to track if they get their shots on …

This study aims to see how well people in Italy stick to their prescribed PCSK9 inhibitor medications for high cholesterol and how effective the treatment is in everyday life. It will follow 5,000 adults already taking these drugs to measure how consistently they take them and ho…

This study is testing a new program that starts heart disease prevention for patients visiting the emergency room for chest pain. The program checks cholesterol, calculates heart risk, and prescribes medication right away, with the goal of preventing future heart attacks and stro…

This study aims to better understand how disorders of blood fats (like cholesterol) develop over time and contribute to heart and blood vessel diseases. Researchers will observe and perform detailed blood tests on up to 2,000 people who have unusually high or low levels of these …

This is an early safety study to see how the body processes a new drug called BKR-017 in people already taking cholesterol-lowering statins. Researchers will give the drug to 10 participants and measure how much of it gets into their blood over time, while carefully checking for …