Massive italian study tracks Real-World use of Cholesterol-Lowering injections
NCT ID NCT05430828
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is following 5,000 Italian patients who are taking PCSK9 inhibitor injections (Repatha or Praluent) for high cholesterol. Researchers want to see how consistently patients take their medication and how well it lowers their LDL cholesterol in real life, not just in a lab. The study will also track side effects and look at differences by age, sex, and other factors.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
PCSK9 inhibitors (evolocumab and alirocumab) given as injections
What this could lead to
If successful, this study could show how well these cholesterol-lowering drugs work in everyday use and help doctors improve treatment plans.
What could go wrong
This is an observational study, not a controlled trial, so it cannot prove cause and effect. Results may not apply outside Italy.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for HYPERCHOLESTEROLEMIA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
AORN dei Colli - Ospedale monaldi
RECRUITINGNaples, 80131, Italy
Contact
-
ASST Grande Ospedale Metropolitano Niguarda
RECRUITINGMilan, 20162, Italy
Contact
Contact
-
Azienda Ospedaliera Ordine Mauriziano Torino
RECRUITINGTorino, 10128, Italy
Contact
-
Azienda Ospedaliera San Camillo-Forlanini
RECRUITINGRoma, 00152, Italy
Contact
-
Azienda Ospedaliera Universitaria San Giovanni di Dio e Ruggi d'Aragona
RECRUITINGSalerno, 84131, Italy
Contact
-
Azienda Ospedaliero-Univeristaria di Parma
RECRUITINGParma, 43126, Italy
Contact
-
Azienda Ospedaliero-Universitaria "Maggiore della Carità"
RECRUITINGNovara, 28100, Italy
Contact
-
Federico II University of Naples, Department of Advanced Biomedical Sciences
RECRUITINGNaples, 80131, Italy
Contact
-
Federico II University of Naples, Department of Translational Medical Sciences
RECRUITINGNaples, 80131, Italy
Contact
-
Ospedale SS Annunziata A.O.U.
RECRUITINGSassari, 07100, Italy
Contact
-
Ospedale di Lecce
RECRUITINGLecce, 73100, Italy
Contact
-
Ospedale di Rivoli
RECRUITINGRivoli, 10098, Italy
Contact
Contact
-
Ospedali dell'Ovest Vicentino
RECRUITINGArzignano, 36071, Italy
Contact
-
Policlinico Casilino
RECRUITINGRoma, 00169, Italy
Contact
-
Policlinico Riuniti Foggia
RECRUITINGFoggia, 71122, Italy
Contact
-
Policlinico Tor Vergata
RECRUITINGRoma, 00133, Italy
Contact
-
Policlinico di Milano Ospedale Maggiore - Fondazione IRCCS Ca' Granda
RECRUITINGMilan, 20122, Italy
Contact
-
Presidio Ospedaliero Maria SS Addolorata
RECRUITINGEboli, 84025, Italy
Contact
-
Presidio Ospedaliero Pescara
RECRUITINGPescara, 65124, Italy
Contact
-
Sapienza University of Rome
WITHDRAWNRoma, 00185, Italy
-
University Magna Graecia of Catanzaro
RECRUITINGCatanzaro, 88100, Italy
Contact
-
University of Bari Aldo Moro
RECRUITINGBari, 70121, Italy
Contact
-
University of Campania Luigi Vanvitelli
RECRUITINGCaserta, 81100, Italy
Contact
-
University of Naples Federico II, Department of Clinical Medicine and Surgery
RECRUITINGNaples, 80131, Italy
Contact
-
University of Siena
RECRUITINGSiena, 53100, Italy
Contact
-
Università degli Studi di Genova
RECRUITINGGenova, 16126, Italy
Contact
-
Università degli Studi di Messina
RECRUITINGMessina, 98122, Italy
Contact