HYPERCHOLESTEROLEMIA

This study looked at whether eating sunflower seeds every day can lower cholesterol in adults. 28 men with high cholesterol ate sunflower seeds for 45 days, and their cholesterol levels were checked before and after. The goal was to see if this simple food change could improve he…

This study tested a new drug called MK-0616 in 303 adults with a genetic condition that causes very high cholesterol (heterozygous familial hypercholesterolemia). Participants took either the drug or a placebo for 24 weeks to see if it safely lowered their LDL (bad) cholesterol. …

This study tested a single pill that combines two cholesterol-lowering medicines (ezetimibe and rosuvastatin) in 305 Chinese adults whose high cholesterol was not well controlled with a statin alone. After 8 weeks, the combo pill lowered LDL (bad) cholesterol more than the statin…

This early study tested a new supplement called BKR-017 in 9 adults with high cholesterol who are already taking statins. The goal was to check how the body processes the supplement and if it is safe. Researchers measured butyrate levels in the blood after a single dose and after…

This study tested two drugs—inclisiran (a shot) and bempedoic acid (a pill)—in 402 adults with high cholesterol and heart disease who were already on statins. The goal was to see which one lowers LDL (bad) cholesterol more. Results will help doctors choose the best treatment to c…

This study looked at adults with high cholesterol who switched from a single statin drug to a combination pill containing pitavastatin and ezetimibe. Over 6,900 participants were followed for 24 weeks to see how much their LDL (bad) cholesterol dropped. The goal was to see if the…

This study tested whether a single pill containing three medicines (ezetimibe, rosuvastatin, and amlodipine) could safely lower both cholesterol and blood pressure in Korean adults with both conditions. 163 participants took either the triple-combination pill or a standard two-dr…

This study looked at how a red yeast rice supplement (LipoCol Forte) helps lower cholesterol in men aged 35 to 55. Researchers checked blood and stool samples to see how the supplement affects gut bacteria and bile acids. The goal was to understand if red yeast rice can safely re…

This study tested whether drinking a calcium-bicarbonate mineral water called Lete could lower LDL (bad) cholesterol in healthy adults with high cholesterol. 160 participants drank either Lete or a regular mineral water for four months. The main goal was to see if Lete reduced ch…

This study tested a new medicine called MK-0616 in about 2,900 adults with high cholesterol. The goal was to see if it could safely lower bad (LDL) cholesterol more than a placebo. Participants took the drug or a dummy pill for 24 weeks, and researchers measured cholesterol chang…

This study tested a new drug called enlicitide (MK-0616) to see if it lowers 'bad' cholesterol better than current medications like ezetimibe and bempedoic acid. About 300 adults with high cholesterol and heart disease risk took part. The goal was to measure cholesterol reduction…

This study tested a new drug called obicetrapib in over 2,500 adults with very high cholesterol or heart disease whose cholesterol was not well-controlled by their current medications. Participants took either the study drug or a placebo pill daily for about 6 months. The main go…

This study tested a new drug, inclisiran, to see how well it lowers 'bad' cholesterol (LDL-C) compared to a placebo and another drug called ezetimibe. The study included 350 adults with high cholesterol who were not taking any other cholesterol medications. Participants received …

This study tested a drug called pemafibrate in 71 adults with high cholesterol who cannot take statins due to side effects. Participants took either a low or high dose of pemafibrate or a placebo for 12 weeks. The goal was to see if the drug safely lowers LDL (bad) cholesterol wi…

This phase 3 study tested a daily pill that combines two drugs, obicetrapib and ezetimibe, to lower LDL (bad) cholesterol in 407 adults with inherited high cholesterol (HeFH) or heart disease (ASCVD). Participants were already on maximum cholesterol-lowering therapy. The main goa…

This study looked at how well the drug Livalozet lowers cholesterol in people with high cholesterol, comparing those who also have diabetes to those who don't. Over 1,500 adults took part, and the main goal was to see how much their LDL (bad) cholesterol dropped after 24 weeks. T…

This study looked at how well inclisiran (Leqvio®) and other cholesterol-lowering medicines work in real life for people with high cholesterol. About 1,868 adults took part, and researchers simply watched their usual care without giving any new treatments. The goal was to underst…

This study tested whether adding inclisiran to standard cholesterol-lowering therapy helps more high-risk patients reach their LDL (bad) cholesterol goals. About 1,770 adults with very high or high cardiovascular risk took part. Results showed that more patients on inclisiran ach…

This study looked at whether drinking Dachundou No Sugar Added Soymilk every day for 8 weeks can lower cholesterol in adults with high cholesterol. 25 participants drank two bottles of soymilk daily. Researchers measured cholesterol, blood pressure, and other health markers. The …

This study looked at how well the drug atostazet lowers cholesterol and affects blood sugar in people aged 65 and older with high cholesterol. Over 600 participants took the drug for 6 months while researchers tracked side effects and changes in glucose levels. The goal was to co…

This study looked at how well two cholesterol-lowering drugs, inclisiran and PCSK9 mAbs, work in real life for Chinese adults with high cholesterol. Researchers analyzed health records from nearly 12,000 patients across three databases. The goal was to see how much these drugs lo…

This study looked at how fat particles called lipoproteins travel in the blood and how they relate to artery hardening. Researchers studied 759 people, including healthy volunteers and those with high cholesterol or other lipid disorders. Participants received injections of label…