Scientists probe fat particles to unlock heart disease secrets

NCT ID NCT00001154

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how fat-carrying particles called lipoproteins work in healthy people and those with high cholesterol or other lipid disorders. Researchers injected tiny, safe amounts of radioactive lipoproteins to track them in the body. The goal was to better understand how these particles contribute to hardening of the arteries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

labeled lipoproteins or apolipoproteins

What this could lead to

If successful, this research could help scientists better understand how fats in the blood contribute to heart disease, potentially guiding future treatments.

What could go wrong

This is an observational and metabolic study, not a treatment trial. It does not test a new therapy, so direct patient benefits are unlikely.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HYPERLIPIDEMIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Dyslipidemias Hypercholesterolemia hyperlipidemia hypoalphalipoproteinemia hypolipoproteinemia inherited lipid metabolism disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States