Scientists probe fat particles to unlock heart disease secrets

NCT ID NCT00001154

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study looked at how fat-carrying particles called lipoproteins work in healthy people and those with high cholesterol or other lipid disorders. Researchers injected tiny, safe amounts of radioactive lipoproteins to track them in the body. The goal was to better understand how these particles contribute to hardening of the arteries.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
labeled lipoproteins or apolipoproteins
What this could lead to
If successful, this research could help scientists better understand how fats in the blood contribute to heart disease, potentially guiding future treatments.
What could go wrong
This is an observational and metabolic study, not a treatment trial. It does not test a new therapy, so direct patient benefits are unlikely.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.