HYPERLIPIDEMIA

This early-stage study is testing a new injectable drug called COR-1004 to see if it's safe for people and to find the right dose. Researchers will give single injections to healthy volunteers with high 'bad' cholesterol (LDL) who aren't taking other cholesterol medications. The …

This study is testing a digital tool called a 'Smart Family Doctor' to see if it helps people better manage their health after heart procedures like bypass surgery or stents. The app uses AI to assist with controlling blood pressure, blood sugar, and cholesterol. About 536 adults…

This study is testing whether a coordinated team approach helps people with heart disease lower their 'bad' cholesterol better than standard care. About 100 participants with heart disease and high cholesterol will be randomly assigned to either receive support from a doctor-phar…

This study is testing if a new drug called enlicitide, when given alongside the standard cholesterol medicine rosuvastatin, works better at lowering 'bad' cholesterol than the standard medicine alone. About 975 adults with high cholesterol will participate. Researchers will compa…

This study is testing whether an investigational injection called SHR-1918 can help lower bad cholesterol and triglycerides in people with high cholesterol who are already taking standard statin pills. About 900 adults will receive either the real injection or a placebo (dummy sh…

This study is testing whether a smartphone app that gives personalized exercise advice can help people with common health conditions like high blood pressure or high blood sugar become more physically active. About 100 adults in China who are not currently active will use the app…

This study is testing a new investigational drug called HRS-1301 to see if it can safely lower high cholesterol levels. It will involve 189 adults with high cholesterol, some of whom have heart disease. Participants will receive either the drug or a placebo for 12 weeks to compar…

This study is testing a 24-week lifestyle program called Inspire HER, designed specifically for Black women at risk for heart disease. The program provides health education, physical activity guidance, and social support resources. Researchers will compare the program's effective…

This study is testing an experimental drug called HRS-7249 to see if it safely lowers high levels of triglycerides, a type of fat in the blood. It will involve about 200 adults with high cholesterol, comparing the drug against a placebo. The main goal is to find the right dose an…

This study is testing if more frequent monitoring and quicker adjustments to cholesterol-lowering medication can help heart disease patients reach their treatment goals. It will enroll 1,000 adults with heart disease to see if this approach lowers 'bad' cholesterol more effective…

This study is testing if a drug called Ursodeoxycholic acid (UDCA) can prevent a common side effect of cholesterol-lowering statins: rising blood sugar levels. Researchers will enroll 128 adults with high cholesterol who are starting statin therapy. Participants will take either …

This study is testing whether a digital health coaching program using smartwatch data can help people improve their lifestyle and prevent chronic diseases. It will enroll 1,700 adults in Singapore who are at risk for or already have conditions like high blood pressure, prediabete…

This study aims to understand how taking many different medications affects the health of older adults living with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will follow 2,000 participants aged 65 and older for two years, asking them to co…

This study aims to understand if a short, 3-month course of high-dose cholesterol medication (statin) can change the fatty buildup (plaque) in heart arteries, as seen on special heart scans. Researchers will follow 140 patients with chest pain but no prior statin use for 24 month…