HYPERLIPIDEMIA

This study tests whether quickly adjusting cholesterol-lowering medications based on frequent blood tests helps more people with heart disease reach their cholesterol goals. About 1,000 adults with high cholesterol and heart disease will have their treatment fine-tuned at a speci…

This study is testing a smartphone app that gives personalized exercise plans to people with high blood pressure, high blood sugar, high cholesterol, and high uric acid (the 'Four Highs'). About 100 adults will use the app for six months to see if it helps them walk more and impr…

This study tests whether an AI-powered smartphone app can help people who have had heart bypass surgery or stents better control their blood pressure, diabetes, and cholesterol. About 536 adults who already have these conditions will use the app or receive standard care. The goal…

This study tests a new medicine called HRS-1301 to see how well it lowers cholesterol in people with high cholesterol. About 189 adults will take either the drug or a placebo for 12 weeks. The main goal is to measure the drop in 'bad' cholesterol (LDL-C) and check for side effect…

This study tests whether a team of healthcare professionals using a special algorithm can help people with heart disease lower their 'bad' cholesterol more effectively than standard care. About 100 adults with a history of heart or blood vessel disease will be randomly assigned t…

This study tests a new medicine called HRS-7249 in 200 adults with high triglycerides (a type of blood fat). The goal is to see if it safely lowers fat levels and to find the best dose. Participants will receive either the drug or a placebo. The trial is for people aged 18 to 79 …

This study tests a program called Inspire HER, designed to help Black women improve their heart health through education, physical activity, and social support. Researchers will enroll 90 Black women aged 30-79 with heart, kidney, or metabolic conditions in the Birmingham, AL are…

This study tests a new medicine called SHR-1918 in 900 adults with high cholesterol and high triglycerides. Participants must already be taking statins. The goal is to see if SHR-1918 can further lower bad cholesterol and blood fats compared to a placebo. The study is currently r…

This study tests whether adding a new medicine called enlicitide to a standard statin (rosuvastatin) lowers bad cholesterol more than a placebo plus the statin. About 975 adults with high cholesterol will take either the combo or a dummy pill for 8 weeks. The main goal is to see …

This early-stage study is testing a new injectable drug called COR-1004 to see if it's safe for people and to find the right dose. Researchers will give single injections to healthy volunteers with high 'bad' cholesterol (LDL) who aren't taking other cholesterol medications. The …

This study tests whether using a smartwatch and a digital health coach can help people at risk for chronic diseases like high blood pressure, diabetes, and obesity become more active. Researchers will enroll 1,700 adults aged 21-75 who have risk factors or early signs of these co…

This study tests if Ursodeoxycholic acid (UDCA) can prevent high blood sugar in people taking statins for high cholesterol. 128 adults aged 18-75 with high LDL but normal blood sugar will take either UDCA or a placebo with their statin for 6 months. Researchers will track changes…

This study looks at how a short course of high-dose statins affects fatty buildup (plaque) in the heart's arteries. About 140 adults with mild heart disease will get either a statin or a placebo, and advanced CT scans will track changes over 3 months. The goal is to understand wh…

This study looks at how taking multiple medications affects the health of elderly people with chronic diseases like heart disease, diabetes, and high blood pressure. Researchers will survey 2000 patients aged 65 and older in Shaanxi Province, China, over two years. The goal is to…