Bile acid pill may shield against statin blood sugar side effect

NCT ID NCT06684106

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 2 times

Summary

This study tests whether ursodeoxycholic acid (UDCA), a drug used for bile duct problems, can stop statins from raising blood sugar. 128 adults with high cholesterol but normal blood sugar will take either UDCA or a placebo alongside atorvastatin for 6 months. Researchers will track changes in blood sugar and safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ursodeoxycholic acid (UDCA)

What this could lead to

If it works, this could offer a way to prevent statin-related blood sugar increases, making statins safer for long-term use.

What could go wrong

This is a small, early-stage trial. The effect may be modest or not appear at all, and UDCA may cause its own side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hyperlipidemia glucose intolerance prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Cardiology, First Affiliated Hospital of Xi'an Jiaotong University

    RECRUITING

    Xi'an, Shaanxi, 710061, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Xi 'an Jiaotong University

    RECRUITING

    Xi'an, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••