Could a natural compound in wheat germ help lower cholesterol and weight?
NCT ID NCT07662330
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study investigates whether taking spermidine, a natural compound found in wheat germ, can improve blood fat levels and body weight in overweight or obese adults with high cholesterol. Participants take either spermidine capsules or a placebo daily for one month. The goal is to see if spermidine safely helps manage cholesterol and weight without medication.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
spermidine
What this could lead to
If it works, this could point toward a natural supplement to help manage cholesterol and weight in people with obesity and high lipids.
What could go wrong
This is a small, early trial with only 50 participants and a short 1-month duration. Results may not apply to everyone, and the supplement may cause side effects like digestive issues.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shanghai Tenth People'S Hospital
RECRUITINGShanghai, Shanghai Municipality, 200072, China
Contact Phone: •••-•••-•••• Email: •••••@•••••