Gut bacteria may tame pancreatitis — probiotic combo put to the test

NCT ID NCT07720232

First seen Jul 22, 2026 · Last updated Jul 23, 2026 · Updated 1 time

Summary

This trial tests whether adding a specific probiotic (Bacillus subtilis and Enterococcus faecium) to standard lipid-lowering therapy can reduce triglyceride levels and inflammation in people hospitalized with pancreatitis caused by very high triglycerides. About 180 adults with mild to moderate disease will receive either standard care alone or standard care plus the probiotic for 28 days. Researchers will measure blood fats, inflammatory markers, and clinical outcomes like hospital stay length and symptom relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a probiotic combination of Bacillus subtilis and Enterococcus faecium (enteric-coated capsules, also known as Meichangan)
What this could lead to
If it works, this could offer a simple, safe add-on treatment to lower triglycerides and reduce inflammation in people with pancreatitis caused by high blood fats.
What could go wrong
This is a single-center, open-label trial, so results may be influenced by bias. The probiotic may not significantly improve outcomes over standard care, and individual responses could vary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Department of Gastroenterology, Zhongshan Hospital, Xiamen University

    RECRUITING

    Xiamen, Fujian, 361004, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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