HYPERLIPIDEMIA

This study tested whether people with high cholesterol who check their own levels at home and get phone support can lower their LDL more than those getting standard care. 70 adults with LDL over 130 mg/dL took part. The idea was that frequent self-testing would help them stick to…

This study tested a new medicine called SHR-1918, given as multiple shots under the skin, in 44 adults with high cholesterol that was not well controlled by current treatments. The goal was to see if it safely lowers 'bad' LDL cholesterol over 24 weeks. This is a phase 2 trial, m…

This early-stage study tested a new drug called HRS-1301 in 82 healthy adults to see if it is safe and how the body processes it. The goal is to eventually use it to control high cholesterol, which is a risk factor for heart disease. Participants took single or multiple doses, an…

This early-stage study tested a single injection of HRS-7249 in 32 to 48 healthy adults with mildly to moderately high cholesterol. The main goal was to check safety and how the drug moves through the body. Participants received either the drug or a placebo, and researchers monit…

This study tested two statins, rosuvastatin and pravastatin, in 86 people with HIV who had high cholesterol and were taking antiretroviral drugs. The goal was to see which drug lowers LDL (bad) cholesterol more safely and effectively over 45 days. Results help doctors choose the …

This study tested a new single pill that combines two common heart medications (pitavastatin and valsartan) against taking them separately. 52 healthy men participated to see how the drugs are absorbed and processed by the body. The goal was to find out if the combination pill wo…

This small study looked at whether taking aspirin before niacin can reduce the uncomfortable flushing (redness and warmth) that niacin often causes. Nine healthy adults with high cholesterol took either aspirin or a placebo for five days, then a single dose of niacin. Researchers…

This study looked at how a new drug, HRS-1301, changes the way the body processes a common cholesterol-lowering medicine (rosuvastatin). Sixteen healthy adults took both drugs in a fixed order, and researchers measured drug levels in the blood. The goal was to gather safety and i…

This study looked at how well people with stable coronary artery disease handle fats (triglycerides) and sugar after a meal. Over 18 months, researchers tracked heart attacks, strokes, and deaths to see if a fat-tolerance test could identify those at higher risk. The goal was to …

This study looked at how fat particles called lipoproteins travel in the blood and how they relate to artery hardening. Researchers studied 759 people, including healthy volunteers and those with high cholesterol or other lipid disorders. Participants received injections of label…