Which statin works best for HIV patients with high cholesterol?
NCT ID NCT00117494
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested two statin drugs, rosuvastatin and pravastatin, in 86 people with HIV who also had high cholesterol. The goal was to see which drug lowered LDL (bad) cholesterol better and was safer when taken with HIV medications. Participants took one of the two statins for 45 days, and researchers measured changes in cholesterol levels and side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Rosuvastatin and pravastatin (statin drugs)
What this could lead to
If one statin works better, it could offer a safer, more effective way to manage cholesterol in people with HIV.
What could go wrong
This is a small, completed Phase 4 trial with only 86 participants. Results may not apply to all HIV patients, and statins can have side effects like muscle pain.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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service de Médecine Interne Hopital Hotel Dieu
Paris, 75004, France