Which statin works best for HIV patients with high cholesterol?

NCT ID NCT00117494

Completed Disease control Sponsor: French National Agency for Research on AIDS and Viral Hepatitis Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested two statin drugs, rosuvastatin and pravastatin, in 86 people with HIV who also had high cholesterol. The goal was to see which drug lowered LDL (bad) cholesterol better and was safer when taken with HIV medications. Participants took one of the two statins for 45 days, and researchers measured changes in cholesterol levels and side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Rosuvastatin and pravastatin (statin drugs)
What this could lead to: If one statin works better, it could offer a safer, more effective way to manage cholesterol in people with HIV.
What could go wrong: This is a small, completed Phase 4 trial with only 86 participants. Results may not apply to all HIV patients, and statins can have side effects like muscle pain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV INFECTIONS HYPERLIPIDEMIA

Contacts and locations

Locations

service de Médecine Interne Hopital Hotel Dieu

Paris, 75004, France

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