HYPERLIPIDEMIA

This study looks at the best way to manage high cholesterol caused by the targeted therapy lorlatinib in people with advanced ALK-positive non-small cell lung cancer. Some participants receive standard cholesterol-lowering drugs, while others get a more intensive combination. The…

This phase 3 trial tests bempedoic acid, a daily pill, in 222 adults with high cholesterol that statins alone can't control. Participants take the drug or a placebo for 12 weeks while staying on their usual cholesterol meds. The main goal is to see how much LDL ('bad') cholestero…

This study tests whether a special clinic where heart, kidney, diabetes, and liver doctors work together can help people with type 2 diabetes and heart disease get better control of their blood pressure and cholesterol. About 150 adults will be randomly assigned to either usual c…

This study tests whether an AI-powered app called 'Smart family doctor' can help people who have had heart surgery (bypass or stent) better control their blood pressure, blood sugar, and cholesterol. About 951 participants from 10-20 hospitals will use the app for personalized he…

This pilot study tests whether a natural supplement called 2-HOBA can reduce harmful oxidized fats in people with high lipoprotein(a), a genetic risk factor for heart disease. Ten adults with elevated Lp(a) will take 2-HOBA capsules for 6 weeks. Researchers will measure changes i…

This study is testing a new, non-invasive way to screen for high cholesterol using a person's breath. Researchers will collect exhaled breath samples from 280 healthy adults and those with high cholesterol. They will analyze the breath for unique chemical patterns to see if the t…

This observational study will follow 100,000 elderly Chinese adults (age 65+) to see how metabolic conditions like diabetes, high blood pressure, and high cholesterol impact the development and progression of chronic kidney disease (CKD). Participants will provide blood and urine…

This early-stage study will test three experimental drugs (AD-231A, AD-231B, and AD-231C) in 55 healthy adults to see how they interact in the body and if they are safe. The drugs are being developed for high blood pressure and high cholesterol. Participants must be between 19 an…

This study aims to create an AI system that combines Traditional Chinese Medicine (TCM) body type data with modern technology to give personalized health advice. Researchers will enroll 195 adults who have all three conditions: high blood pressure, high blood sugar, and high chol…