Could a simple supplement tame a stubborn heart risk?
NCT ID NCT07198009
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether a natural supplement called 2-HOBA can reduce harmful oxidized fats in people with high lipoprotein(a), a genetic risk factor for heart disease. Ten adults with elevated Lp(a) will take 2-HOBA capsules for 6 weeks. Researchers will measure changes in blood markers of oxidation, inflammation, and clotting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- 2-HOBA (Hobamine), a dietary supplement
- What this could lead to
- If it works, this could point toward a simple supplement to lower heart disease risk in people with high lipoprotein(a).
- What could go wrong
- This is a very small, early pilot study with only 10 participants and no placebo group, so results may not be conclusive or generalizable.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Lipid Clinic at Brown University Health
Providence, Rhode Island, 02914, United States
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