Can a daily pill tame a hidden heart risk?

NCT ID NCT07745114

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This early-stage trial tests an experimental oral drug called SAL0137 in healthy adults, some with elevated Lp(a), a genetic risk factor for heart disease. The study aims to check the drug's safety, how the body processes it, and its effect on Lp(a) levels. Participants receive either the drug or a placebo, with some taking a single dose and others taking it daily for two weeks.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
SAL0137 tablets
What this could lead to
If successful, this could lead to a daily pill that lowers Lp(a), a risk factor for heart disease, potentially reducing cardiovascular risk.
What could go wrong
This is an early-phase trial focused on safety and dosing, not effectiveness. The drug may not lower Lp(a) as hoped or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The First Affiliated Hospital of ANHUI Medical University

    Hefei, Anhui, 230088, China

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