Can a common antifungal change how an experimental drug acts?
NCT ID NCT07764692
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This Phase 1 trial is investigating whether itraconazole, an antifungal drug, affects the levels of an experimental drug called HS-10504 in the body. Healthy adult volunteers will receive HS-10504 alone and then again while taking itraconazole, allowing researchers to compare how the drug is absorbed and cleared. The goal is to understand potential drug interactions and inform future dosing recommendations.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- HS-10504 (an experimental drug) and itraconazole (an antifungal medication)
- What this could lead to
- If itraconazole alters HS-10504 levels, this could guide dosing adjustments for future studies of HS-10504.
- What could go wrong
- This is a small, early-stage study in healthy people, not patients, so results may not predict effects in disease states. Drug interactions may vary.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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