New pill could help millions with stubborn high cholesterol

NCT ID NCT07623915

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase 3 trial tests bempedoic acid, a daily pill, in 222 adults with high cholesterol that statins alone can't control. Participants take the drug or a placebo for 12 weeks while staying on their usual cholesterol meds. The main goal is to see how much LDL ('bad') cholesterol drops. If successful, it could provide a new option for people at risk of heart disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
bempedoic acid
What this could lead to
If it works, this could offer a new daily pill option for people with high cholesterol that statins alone can't manage.
What could go wrong
This is still a phase 3 trial, so results are not yet known. The drug may not lower cholesterol enough or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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Other studies related to the condition(s) this trial covers.