HYPERCHOLESTEROLEMIA

This study follows about 116 people who received an experimental gene-editing therapy for heart disease or high cholesterol. Researchers will monitor participants for 15 years to check for side effects and measure changes in cholesterol levels. The goal is to understand the long-…

This study tests a new way to help cancer survivors manage other health problems like high blood pressure, diabetes, and high cholesterol. About 800 adults with certain cancers and at least one heart-related condition will be enrolled. Their primary care doctors will work more cl…

This study tests a drug called inclisiran in about 345 Asian patients with high cholesterol and heart disease or high risk for it. The drug is given as an injection alongside standard statin therapy. The main goal is to see if it safely lowers 'bad' LDL cholesterol more than a pl…

This study looks at different methods to help people with high cholesterol and heart disease get their LDL ("bad") cholesterol to recommended levels. About 300 adults with or at high risk for artery disease will take part. Researchers will compare approaches to improve use of cho…

This study tested a combination of two cholesterol-lowering medicines (Pitavastatin and Ezetimibe) in 88 adults with high cholesterol and high triglycerides. The goal was to see if the combo works better than Pitavastatin alone at reducing LDL (bad) cholesterol over 8 weeks, with…

This study looks at the long-term safety and effectiveness of the drug MK-0616 (enlicitide decanoate) in adults with high cholesterol. It includes 3000 people who already completed an earlier study with the same drug. The main goals are to track side effects and see how well the …

This study tests whether a 30-minute educational website helps people who stopped taking statins due to muscle symptoms make informed decisions about restarting the medication. About 816 participants will either use the website or receive usual care. Researchers will track how ma…

This study follows 5,000 adults with high cholesterol who are taking bempedoic acid (alone or with ezetimibe) in everyday medical practice. Researchers will track how well the drug lowers cholesterol, any side effects, and heart-related events over one year or more. The goal is t…

This study looks at how ketogenic diets (like the modified Atkins diet) impact heart health in adults with epilepsy. Researchers will measure cholesterol, blood pressure, weight, and artery thickness over 12 months. About 105 adults aged 18 and older who are already on or startin…

This study checks how often hospital staff have high levels of a type of cholesterol called Lp(a), which can raise the risk of heart disease. About 2,800 healthcare workers and their family members will give blood samples. The goal is to see how common this condition is in differ…