Gene-Editing heart therapy under 15-Year watch

NCT ID NCT06112327

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study follows 116 people who received an experimental gene-editing therapy for heart disease or high cholesterol. Researchers will monitor them for 15 years to track any side effects and how well the treatment controls cholesterol levels. The goal is to understand the long-term safety and effectiveness of this one-time therapy.

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Conditions

The condition(s) this trial relates to.

atherosclerosis atherosclerotic cardiovascular disease cardiovascular disorder familial hypercholesterolemia Hypercholesterolemia hyperlipidemia Hyperlipoproteinemia Type II

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Study Center

    Auckland, New Zealand

  • Clinical Study Center

    Christchurch, New Zealand

  • Clinical Study Center

    London, United Kingdom