HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
Clinical trials for HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA explained in plain language.
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Gene-Editing shot could slash cholesterol for good
Disease control Recruiting nowThis early-stage trial tests a single IV dose of VERVE-102, a gene-editing drug designed to permanently lower LDL (bad) cholesterol by turning off a specific gene in the liver. It involves 85 adults with inherited high cholesterol or early heart disease who still need lower chole…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
Phase: PHASE1 • Sponsor: Verve Therapeutics, Inc. • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Aggressive cholesterol drugs may shrink artery plaque in young patients
Disease control Recruiting nowThis study tests whether starting strong cholesterol-lowering therapy early can reverse plaque buildup in the arteries of young adults (ages 18-50) with familial hypercholesterolemia, a genetic condition causing very high cholesterol. Researchers will use CT scans to measure chan…
Matched conditions: HETEROZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA
Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC