ATHEROSCLEROTIC CARDIOVASCULAR DISEASE

This study continues testing an experimental drug called pelacarsen for people with high levels of a specific blood fat (Lp(a)) and established heart disease. It's open only to people who successfully completed earlier trials of this medication. The main goal is to monitor the dr…

This study is testing an investigational drug called CSL300 (clazakizumab) to see if it can lower the risk of heart attacks and death in people with end-stage kidney disease who are on dialysis. The trial will enroll over 2,300 adults who have both kidney failure and either heart…

This large study is testing whether a new injectable medication, maridebart cafraglutide, can help prevent serious heart problems in people who already have heart disease and are overweight or obese. It will compare the drug to a placebo (inactive shot) in over 12,000 participant…

This study is testing whether a special education and support program helps people with high cholesterol and a high risk of heart disease reach their cholesterol goals. About 326 adults in Abu Dhabi who are already on standard cholesterol medication will either receive the educat…

This study is testing whether telling people their genetic risk for high blood pressure helps them manage it better. Researchers will enroll 300 adults aged 18-55 who already have high blood pressure and poor heart health. Half will receive their genetic risk score and counseling…

This early-stage study aims to test the safety of an experimental drug called UDP-003 in healthy volunteers and people with a history of heart attacks or chest pain. Researchers want to see how the body processes the drug and get a first look at whether it might reduce dangerous …

This study is testing whether adding a daily fish oil supplement to the standard medication metformin can better protect the heart health of women with Polycystic Ovary Syndrome (PCOS). It will involve 146 overweight or obese women with PCOS who are already at higher risk for hea…