Heart drug showdown: which statin spares your blood sugar?
NCT ID NCT05705804
First seen Jul 07, 2026 · Last updated Jul 08, 2026 · Updated 1 time
Summary
This trial compares three cholesterol-lowering treatments—pitavastatin alone, pitavastatin plus ezetimibe, and atorvastatin—to see how they affect blood sugar control in people with heart disease and metabolic syndrome (but not diabetes). The main focus is on insulin resistance after 24 weeks. The goal is to find a statin option that protects the heart without raising diabetes risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Pitavastatin, ezetimibe, atorvastatin
- What this could lead to
- If pitavastatin or the combination proves better for blood sugar, doctors may choose these options to lower cholesterol without worsening diabetes risk.
- What could go wrong
- This is a moderate-sized trial comparing known drugs, so results may not apply to all patients. The effect on glucose is a secondary outcome, and differences may be small.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Yonsei University Health System, Severance Hospital
RECRUITINGSeoul, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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