ATHEROSCLEROTIC CARDIOVASCULAR DISEASE

This large study is testing whether a new drug called olpasiran can reduce the risk of heart attacks, heart-related deaths, and emergency heart procedures in people who already have heart disease and high levels of a specific blood fat called lipoprotein(a). About 7,300 participa…

This study is observing 600 Belgian patients with heart disease who are taking the cholesterol-lowering injection inclisiran along with their standard medications. Researchers are tracking how well the drug lowers 'bad' cholesterol (LDL-C) in real-world doctor's offices, not a co…

This large study is testing whether a new cholesterol-lowering injection called inclisiran can safely reduce the risk of future heart attacks, strokes, and related heart problems in people who already have heart disease. Over 16,000 participants received either the injection or a…

This large study is testing if a new drug called inclisiran can help prevent serious heart problems in people who already have heart disease. Over 17,000 participants will receive either the drug or a placebo as a shot every six months, on top of their standard cholesterol medica…

This study is testing whether adding a cholesterol-lowering injection called inclisiran to usual care helps people with heart disease or high risk for it reach their cholesterol goals. It focuses on including diverse participants, such as women and people from racial/ethnic minor…

This large study is testing whether berberine, a compound from plants, can help prevent heart disease and type 2 diabetes in adults at high risk. Over 2,000 participants in China will take either berberine or a placebo pill for three years, alongside lifestyle advice. Researchers…

This study aimed to see if telling patients and their doctors about artery calcium found during routine lung cancer scans could help prevent heart attacks, strokes, or death. It planned to compare this notification approach against standard care reminders. The trial was withdrawn…

This study aimed to understand how powerful cholesterol-lowering drugs (PCSK9 inhibitors) affect inflammation in the arteries of people with heart disease. Researchers planned to use a special imaging scan to measure inflammation in participants already on standard statin medicat…