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New shot cuts bad cholesterol in asian heart patients

NCT ID NCT04765657

Ongoing Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a drug called inclisiran in about 345 Asian patients who have heart disease or are at high risk and still have high LDL (bad) cholesterol despite taking statins. The goal is to see if inclisiran lowers LDL cholesterol more than a placebo over about 11 months, and to check its safety. Participants continue their usual diet and statins during the trial.

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Conditions

The condition(s) this trial relates to.

atherosclerotic cardiovascular disease Dyslipidemias Hypercholesterolemia hyperlipidemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERCHOLESTEROLEMIA

Contacts and locations

Locations

  • Novartis Investigative Site

    Lanzhou, Gansu, 730030, China

  • Novartis Investigative Site

    Foshan, Guangdong, 528000, China

  • Novartis Investigative Site

    Guangzhou, Guangdong, 510080, China

  • Novartis Investigative Site

    Shijiazhuang, Hebei, 050000, China

  • Novartis Investigative Site

    Baotou, Inner Mongolia, 014040, China

  • Novartis Investigative Site

    Hohhot, Inner Mongolia, 010017, China

  • Novartis Investigative Site

    Nanjing, Jiangsu, 210008, China

  • Novartis Investigative Site

    Nanjing, Jiangsu, 211166, China

  • Novartis Investigative Site

    Nantong, Jiangsu, 226000, China

  • Novartis Investigative Site

    Suzhou, Jiangsu, 215004, China

  • Novartis Investigative Site

    Xuzhou, Jiangsu, 221003, China

  • Novartis Investigative Site

    Changchun, Jilin, 130000, China

  • Novartis Investigative Site

    Changchun, Jilin, 130021, China

  • Novartis Investigative Site

    Jinan, Shandong, 250013, China

  • Novartis Investigative Site

    Jinshan, Shanghai Municipality, 201508, China

  • Novartis Investigative Site

    Taiyuan, Shanxi, 030002, China

  • Novartis Investigative Site

    Xian, Shanxi, 710061, China

  • Novartis Investigative Site

    Tianjin, Tianjin Municipality, 300121, China

  • Novartis Investigative Site

    Hangzhou, Zhejiang, 310014, China

  • Novartis Investigative Site

    Beijing, 100034, China

  • Novartis Investigative Site

    Beijing, 100039, China

  • Novartis Investigative Site

    Beijing, 100050, China

  • Novartis Investigative Site

    Beijing, 100191, China

  • Novartis Investigative Site

    Shanghai, 200032, China

  • Novartis Investigative Site

    Shanghai, 200040, China

  • Novartis Investigative Site

    Shanghai, 200080, China

  • Novartis Investigative Site

    Shanghai, 200120, China

  • Novartis Investigative Site

    Tianjin, 300052, China

  • Novartis Investigative Site

    Tianjin, 300140, China

  • Novartis Investigative Site

    Xiamen, 361004, China

  • Novartis Investigative Site

    Singapore, 119074, Singapore

  • Novartis Investigative Site

    Singapore, 169609, Singapore

  • Novartis Investigative Site

    Wŏnju, Gangwon-do, 26427, South Korea

  • Novartis Investigative Site

    Incheon, Korea, 405 760, South Korea

  • Novartis Investigative Site

    Seoul, Korea, 02841, South Korea

  • Novartis Investigative Site

    Seoul, Korea, 03080, South Korea

  • Novartis Investigative Site

    Seoul, Seoul, 06351, South Korea

  • Novartis Investigative Site

    Seoul, South Korea, 110-746, South Korea

  • Novartis Investigative Site

    Gwangju, 61469, South Korea

  • Novartis Investigative Site

    Seoul, 03722, South Korea

  • Novartis Investigative Site

    Seoul, 05505, South Korea

  • Novartis Investigative Site

    Kaohsiung City, 80756, Taiwan

  • Novartis Investigative Site

    Taipei, 10002, Taiwan

  • Novartis Investigative Site

    Taipei, 11217, Taiwan

  • Novartis Investigative Site

    Taipei, 11220, Taiwan