Can lowering cholesterol more aggressively help seniors with heart disease?

NCT ID NCT05361421

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two cholesterol-lowering strategies in adults aged 75 and older who have heart or blood vessel disease. One group aims for a very low LDL cholesterol target (below 55 mg/dL) using high-intensity statins, while the other receives standard moderate-intensity statin therapy. The goal is to see if the more aggressive approach reduces the risk of heart-related death, heart attacks, strokes, or the need for procedures to open blocked arteries.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Yonsei University Health System, Severance Hospital

    Seoul, South Korea

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