ATHEROSCLEROTIC CARDIOVASCULAR DISEASE

This study tested a new drug called AZD0780 to see if it can lower blood pressure in people with heart disease or related risks who also have high cholesterol. About 202 adults took part, and they received either the drug or a placebo for 4 weeks. The main goal was to measure cha…

This study tested a new drug called obicetrapib in over 2,500 adults with very high cholesterol or heart disease whose cholesterol was not well-controlled by their current medications. Participants took either the study drug or a placebo pill daily for about 6 months. The main go…

This early-stage study tested a new drug called AZD4144 in 29 adults with both heart disease and chronic kidney disease. The goal was to check if the drug is safe and if it lowers certain markers of inflammation in the blood. Participants took either the drug or a placebo for 4 w…

This study tested an experimental drug called olezarsen in 154 adults with very high triglycerides (a type of blood fat) and either heart disease or a high risk for it. The goal was to see if the drug could safely lower triglyceride levels more than a placebo over 6 and 12 months…

This study tested whether adding ezetimibe early to atorvastatin works better than atorvastatin alone for lowering LDL (bad) cholesterol in people at very high risk for heart problems. It involved 137 adults with atherosclerotic cardiovascular disease. The goal was to see if the …

This study looked at whether aiming for a very low LDL-cholesterol level (below 55 mg/dL) is better than a standard target (below 70 mg/dL) in people with heart or blood vessel disease. About 3,000 adults in Asia took either a statin alone or a statin plus ezetimibe to lower thei…

This study looked at nearly 40,000 people with a history of heart disease to measure their levels of lipoprotein(a), a fatty substance in the blood that can increase heart risk. Researchers wanted to see how common high levels are and whether they differ by age, sex, or region. T…

This study looked at whether real-world data can be used to compare two diabetes drugs, tirzepatide and sitagliptin, for preventing heart attacks, strokes, or death in people with type 2 diabetes and heart disease. Over 49,000 participants were included, but the goal was not to f…

This completed study surveyed 608 heart and kidney specialists to understand their awareness and use of a blood test called hsCRP, which measures inflammation. The goal was to learn what doctors think about inflammation's role in managing atherosclerotic cardiovascular disease, c…