Heart study tests if lowering 'Bad' cholesterol even more saves lives

NCT ID NCT04626973

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looked at 3048 adults with heart or blood vessel disease to see if lowering LDL ('bad') cholesterol to a very low level (below 55 mg/dL) is better than the standard target (below 70 mg/dL). Participants received either a statin alone or a statin plus ezetimibe. The goal was to reduce the risk of heart attacks, strokes, and other major events. The trial is complete and results will help guide cholesterol treatment in Asian populations.

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Conditions

The condition(s) this trial relates to.

atherosclerosis atherosclerotic cardiovascular disease coronary artery disorder Dyslipidemias

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Division of Cardiology, Yonsei Cardiovascular Hospital, Yonsei University College of Medicine

    Seoul, South Korea