New drug targets inflammation in heart and kidney patients
NCT ID NCT06675175
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-stage trial tested a new drug called AZD4144 in 29 people who have both heart disease and chronic kidney disease. The main goal was to see if the drug is safe and if it lowers certain markers of inflammation in the blood. The study compared the drug against a placebo over 4 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
AZD4144
What this could lead to
If successful, this could point toward a new way to reduce inflammation in people with both heart and kidney disease.
What could go wrong
This is a very early Phase 1 trial with only 29 people, so it is mainly checking safety, not yet proving the drug works. Many early-stage drugs do not move forward.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Research Site
Glendale, California, 91203, United States
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Research Site
Daytona Beach, Florida, 32117, United States
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Research Site
Jacksonville, Florida, 32216, United States
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Research Site
Miami, Florida, 33125, United States
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Research Site
Port Orange, Florida, 32127, United States
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Research Site
Tampa, Florida, 33603, United States
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Research Site
Farmington Hills, Michigan, 48334, United States
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Research Site
The Bronx, New York, 10455, United States
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Research Site
Sherman, Texas, 75092, United States
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Research Site
Pleven, 5800, Bulgaria
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Research Site
Sofia, 1527, Bulgaria
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Research Site
Gyöngyös, 3200, Hungary
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Research Site
Kistarcsa, 2143, Hungary
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Research Site
Bucharest, 11658, Romania
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Research Site
Cluj-Napoca, 400006, Romania