ATHEROSCLEROTIC CARDIOVASCULAR DISEASE

This study tests whether secukinumab, a drug that blocks inflammation, can reduce the risk of major heart problems and kidney decline in people with cardiorenal metabolic syndrome and hardened arteries. About 100 adults will receive either secukinumab injections plus standard car…

This study compares two cholesterol-lowering strategies in 6,000 Chinese patients with very high-risk heart disease. One group aims for ultra-low LDL cholesterol below 1.0 mmol/L, while the other targets a moderate level of 1.0-1.39 mmol/L. Researchers will track heart attacks, s…

This trial tests whether a smartphone app called Antshrike, paired with a smartwatch, can predict heart attacks or strokes within 3-4 days in people at high risk. Participants aged 40 to 79 with existing heart disease or elevated risk will wear the smartwatch for 18 months while …

This study will use heart scans and blood tests to check for early signs of heart disease in 650 adult survivors of childhood cancer. The goal is to better understand who is at highest risk due to past cancer treatments like radiation or chemotherapy. Results will be compared to …

This study follows 3,000 adults in Qatar—both citizens and long-term residents—to track how cardiometabolic conditions like diabetes and heart disease develop over time. Participants are grouped by blood sugar status (normal, pre-diabetes, or diabetes) and monitored for major car…